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High-Yield Revision Tables — Scroll Through All 17

Resuscitation Council UK & NICE Guidelines

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Table 1 — Adult ALS: Cardiac Arrest Algorithm

StepActionKey Details
InitialSafety → Check response → Shout for helpAttach defibrillator/monitor immediately
CPR30:2 ratio, 100–120/min, 5–6 cm depthMinimise interruptions; continuous if advanced airway
Rhythm checkEvery 2 minutes
SHOCKABLE (VF/pVT)1 shock → Immediate CPR 2 min150–200 J biphasic or 360 J monophasic
After 3rd shock: Adrenaline 1 mg IV/IOThen every 3–5 min
After 3rd shock: Amiodarone 300 mg IVRepeat 150 mg after 5th shock
NON-SHOCKABLE (PEA/Asystole)Immediate CPR 2 minAdrenaline 1 mg IV/IO ASAP, then every 3–5 min
4 HsHypoxia, Hypovolaemia, Hypo/Hyperkalaemia, HypothermiaTreat identified cause
4 TsThrombosis, Tension pneumothorax, Tamponade, ToxinsThrombolysis for massive PE/MI
ROSCABCDE; SpO2 94–98%; Normocapnia; 12-lead ECGTTM 32–36°C; PCI if indicated

Table 2 — Adult Tachycardia Algorithm

FeatureStableUnstable
DefinitionNo shock, syncope, ischaemia, severe HFAny life-threatening feature present
ImmediateAssess QRS widthSynchronised DC shock up to 3 attempts; sedate if conscious
Narrow RegularVagal manoeuvres → Adenosine 6 mg → 12 mg → 18 mg IV; if ineffective: Verapamil or beta-blocker
Narrow IrregularProbable AF: Rate control (beta-blocker, Digoxin, Amiodarone if HF); anticoagulate if >48 h
Broad RegularVT/uncertain: Amiodarone 300 mg IV over 10–60 min; if known SVT+BBB treat as narrow
Broad IrregularAF+BBB: treat as irregular narrow; Torsades: Magnesium 2 g IV over 10 min

Table 3 — Adult Bradycardia Algorithm

StatusHeart RateManagement
Stable<60 bpmObserve; treat underlying cause
Unstable (shock, syncope, MI, HF)AnyAtropine 500 mcg IV
Atropine ineffectiveRepeat to max 3 mg OR Isoprenaline 5 mcg/min OR Adrenaline 2–10 mcg/min OR Transcutaneous pacing
Risk of asystoleRecent asystole / Mobitz II / Complete heart block + broad QRS / Ventricular pause >3 s → Atropine → Interim → Pacing

Table 4 — Adult Choking Algorithm

SeverityCoughConscious?Action
MILDEffectiveYesEncourage cough; monitor for deterioration
SEVEREIneffectiveYes5 back blows → 5 abdominal thrusts (repeat)
SEVEREIneffectiveNoStart CPR

Table 5 — Paediatric Advanced Life Support (PALS)

ParameterDetails
Initial CPR5 rescue breaths, then 15:2 compression:ventilation
Compression depthAt least 1/3 anterior-posterior chest depth
Rate100–120/min
Shockable (VF/pVT)1 shock 4 J/kg → CPR 2 min → Adrenaline 10 mcg/kg IV/IO after 3rd shock, then every 3–5 min; Amiodarone 5 mg/kg after 3rd shock; repeat once after 5th
Non-shockableCPR immediately; Adrenaline 10 mcg/kg ASAP, then every 3–5 min
Ventilation (with ETT)Infants: 25/min • 1–8 yrs: 20/min • 8–12 yrs: 15/min • >12 yrs: 10–12/min
Max dosesAdrenaline 1 mg • Amiodarone 300 mg

Table 6 — Paediatric Bradycardia & Tachycardia

ArrhythmiaDefinitionManagement
Bradycardia<1 yr: <80 bpm; >1 yr: <60 bpmO2; if HR <60 + poor perfusion → CPR; Atropine 20 mcg/kg (max 600 mcg); Adrenaline if no response
Sinus TachycardiaGradual onset; infant 180–220, child 160–180Treat cause (fever, pain, hypovolaemia)
SVTAbrupt onset; infant >220, child >180Vagal manoeuvres → Adenosine 100–300 mcg/kg (max 500 mcg) → 12 mg; synchronised cardioversion if unstable
VTWide complex, regularPulse + unstable: synchronised cardioversion; Pulseless: treat as VF (unsynchronised)
AF (irregular narrow)Rate control; anticoagulate if >48 h

Table 7 — Newborn Life Support (NLS)

Time/StepActionCritical Values
BirthDelay cord clamping if possible; Dry, wrap, stimulateStart clock
60 secondsAssess: Colour, tone, breathing, heart rate
If gasping/apnoeic5 inflations (30 cm H2O), start in airPreterm: Consider CPAP
Chest not movingCheck mask/position; 2-person support; suction; LMA/ETT; repeat inflations
HR <60/min after 30 s ventilation3:1 compressions:ventilation; 100% O2; intubateAdrenaline 10 mcg/kg (UVC or IO)
Preterm O228–31 weeks: 21–30%; <28 weeks: 30%
Target SpO22 min: 65% • 5 min: 85% • 10 min: 90%

Table 8 — Obstetric Cardiac Arrest

FeatureSpecific Consideration
PositioningManual uterine displacement to left OR left lateral tilt 15–30°
TeamsSeparate team for mother AND neonate if ≥20 weeks gestation
DefibrillationSafe in pregnancy; standard energies
Emergency hysterotomy≥20 weeks; perform by 5 min if no ROSC; immediately if fatal maternal injuries
Specific causes4 Hs + 4 Ts PLUS: AFE, eclampsia, peripartum cardiomyopathy, uterine rupture, concealed haemorrhage
DrugsMagnesium 4 g IV (eclampsia); Tranexamic acid 1 g (haemorrhage); Intralipid (local anaesthetic toxicity)

Table 9 — Difficult Airway: CICO Algorithm

PlanActionKey Points
ADirect laryngoscopy (max 3 attempts)Maintain oxygenation; bougie/stylet; video laryngoscopy
1st failureCall HELP; prepare FONA set
B / CRescue oxygenation: 2nd gen SGA OR facemaskMax 3 attempts each; change device/operator/size
Declare CICO→ Plan D: FONA (scalpel cricothyroidotomy)
D Step 1Laryngeal handshake; identify cricothyroid membraneScalpel no.10/20 • Bougie ≤14 Fr • Cuffed tube 5.0–6.0 mm
D Step 2Transverse stab incision
D Step 3Turn blade 90° (sharp edge caudad)
D Step 4Slide bougie along blade into trachea
D Step 5–6Railroad tube; inflate cuff; confirm with capnography

Table 10 — Tracheostomy Emergency Management

ScenarioAction
Patient NOT breathingCall resuscitation team; CPR if no pulse
Assess patencyRemove speaking valve/cap; remove inner tube
Suction catheter passes? YESPatent → Suction, ventilate if needed, ABCDE
Suction catheter passes? NODeflate cuff; Look, listen, feel at mouth AND stoma
Stable/improving? YESPartial obstruction → Continue ABCDE
Stable/improving? NOREMOVE TRACHEOSTOMY TUBE
Still not breathing — PrimaryOral airway manoeuvres; cover stoma; BVM
Still not breathing — SecondaryOral intubation OR stoma intubation (6.0 cuffed ETT)

Table 11 — NICE ACS: STEMI vs NSTEMI

FeatureSTEMINSTEMI / Unstable Angina
ImmediateAspirin 300 mg; NO routine GPI/fibrinolysis if primary PCI plannedAspirin 300 mg; Fondaparinux (unless high bleeding risk/immediate angiography)
ReperfusionPrimary PCI vs FibrinolysisRisk stratification (GRACE score)
PCI timing<12 h: Immediate; >12 h with ongoing ischaemia/shockIntermediate/high risk: <72 h; Low risk: Conservative
AntiplateletPrasugrel + Aspirin (no OAC); Ticagrelor if prasugrel contraindicatedTicagrelor + Aspirin; Clopidogrel if high bleeding risk/OAC
AnticoagulationUnfractionated heparin with bailout GPIPer protocol
OAC + AntiplateletClopidogrel (replace prasugrel/ticagrelor) + OAC; consider aspirin

Table 12 — NICE AF: Stroke Prevention (CHA2DS2-VASc)

ScoreAction
≥2 (men) / ≥3 (women)Offer oral anticoagulant
1 (men) / 2 (women)Consider oral anticoagulant
0 (men) / 1 (women)Do not offer; review at 65 or if comorbidities develop
First choiceDOAC (Apixaban, Rivaroxaban, Dabigatran, Edoxaban)
If DOAC contraindicatedWarfarin — target INR 2.5 (range 2–3)
If anticoagulation contraindicatedLeft atrial appendage occlusion

Table 13 — NICE AF: Rate vs Rhythm Control

StrategyIndicationsFirst-line Drugs
Rate controlFirst-line unless: reversible cause, HF caused by AF, new-onset AF, atrial flutter suitable for ablationBeta-blocker (not sotalol) OR rate-limiting CCB; Digoxin if sedentary; avoid amiodarone long-term
Rhythm controlFirst-line in above exceptions; symptoms despite rate control
Paroxysmal AFBeta-blocker; pill-in-pocket flecainide if no structural heart disease
Persistent AF >48 hAnticoagulate 3 weeks before / 4 weeks after cardioversion; OR TOE-guided
Acute + instabilityEmergency electrical cardioversion (don't delay for anticoagulation)

Table 14 — NICE VTE: DVT & PE Diagnosis

ConditionWells ScoreNext Step
DVT Likely≥2Proximal leg vein USS within 4 h; OR D-dimer + interim anticoagulation → scan within 24 h
DVT Unlikely≤1D-dimer in 4 h; +ve → scan; −ve → stop anticoagulation
PE Likely>4Immediate CTPA; OR interim anticoagulation
PE Unlikely≤4D-dimer in 4 h; +ve → CTPA; −ve → stop anticoagulation

Table 15 — NICE VTE: Anticoagulation Treatment

Patient GroupAnticoagulantDuration
Standard (no renal impairment/cancer/APS/instability)Apixaban or Rivaroxaban (1st line); OR LMWH → Dabigatran/Edoxaban; OR LMWH + VKA≥3 months
Renal impairment CrCl 15–50Apixaban, Rivaroxaban, or LMWH → Edoxaban/Dabigatran (≥30); OR LMWH/UFH + VKA≥3 months
CrCl <15LMWH or UFH; OR LMWH/UFH + VKA≥3 months
Active cancerConsider DOAC; OR LMWH; OR LMWH + VKA3–6 months
Antiphospholipid syndrome (triple positive)LMWH + VKALong-term
PE with haemodynamic instabilityContinuous UFH; consider thrombolysis

Table 16 — Post-Resuscitation Care (ROSC)

SystemTarget / Action
AirwayAdvanced airway if needed; waveform capnography
BreathingSpO2 94–98%; Normocapnia (PaCO2 35–45 mmHg)
CirculationSBP >100 mmHg; 12-lead ECG; reliable IV access; consider vasopressors
TemperatureTTM 32–36°C for ≥24 h; prevent fever for 72 h
NeurologySedation; control shivering; delay prognostication ≥72 h
InvestigationsEchocardiography; CT brain if non-cardiac cause; CTPA if PE suspected
Coronary reperfusionEmergency angiography/PCI if ST elevation or suspected cardiac cause
Secondary preventionICD if indicated; screen inherited disorders; risk factor management

MRCEM Exam — Key Numbers to Memorise

ParameterValue
CPR compression rate100–120 /min
CPR compression depth (adult)5–6 cm
CPR ratio (adult)30:2
CPR ratio (paediatric, 2 rescuers)15:2
Shock energy — adult biphasic150–200 J
Shock energy — adult monophasic360 J
Shock energy — paediatric4 J/kg
Adrenaline frequencyEvery 3–5 minutes
Amiodarone (adult)300 mg, then 150 mg
Amiodarone (paediatric)5 mg/kg, repeat once
Atropine max (adult)3 mg
Newborn ventilation pressure30 cm H2O initial; 25 cm H2O preterm
Targeted temperature management32–36°C
Emergency hysterotomy timingBy 5 minutes if no ROSC
CHA2DS2-VASc — anticoagulate≥2 (men) / ≥3 (women)
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Sample Question — See What to Expect
MRCEM Primary Pharmacology ⭑⭑ Medium Example Question
Select one best answer

A 28-year-old woman presents to the Emergency Department with a suspected paracetamol overdose taken 3 hours ago. She is haemodynamically stable. Her serum paracetamol level is above the treatment line on the nomogram. Which of the following is the most appropriate initial management?

A
Activated charcoal 50 g orally
B
Intravenous N-acetylcysteine (NAC) infusion
C
Methionine 2.5 g orally four times a day
D
Observe and repeat paracetamol level at 8 hours
E
Urgent liver transplant referral
Answer & Explanation
Correct answer — B. Intravenous N-acetylcysteine (NAC) infusion
NAC is the treatment of choice for paracetamol overdose when the level falls above the treatment line on the Rumack-Matthew nomogram. It works by replenishing glutathione stores, preventing the toxic metabolite NAPQI from binding to hepatocytes.

Activated charcoal (A) is only useful within 1–2 hours of ingestion. At 3 hours, it offers little benefit and is not the priority when NAC is clearly indicated.

Methionine (C) is an oral alternative when IV access is unavailable, but it is second-line and less effective. It is rarely used in UK emergency practice.

Observation alone (D) is inappropriate when the level is above the treatment line — active treatment is required, not watchful waiting.

Transplant referral (E) is only considered in established acute liver failure meeting King's College Criteria — far too premature at 3 hours post-ingestion. 🧠 High-yield fact: The MHRA 2012 guidelines simplified the paracetamol nomogram to a single treatment line at 100 mg/L at 4 hours. All patients above this line receive the standard 3-bag NAC regimen (200 mg/kg over 4 h → 100 mg/kg over 16 h).
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